Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

Blog Article

one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity related to bortezomib, a proteasome inhibitor used in the treatment of multiple myeloma. Its synthesis or review is critical for ensuring the purity and protection on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug Employed in the remedy of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A essential compound within the synthesis of imatinib, a drug that targets unique forms of most cancers, which includes Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats various cancers for instance breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are definitely intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their research is important for optimizing the creation process and guaranteeing higher purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is utilized to deal with breast most cancers, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the remedy of breast most cancers. Many intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-16-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers for instance ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized 2-difluoro-D-erythro-pentofuranose-3 in the cure of colorectal most cancers and little mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-82-9): This compound is involved with the synthesis of adamantane derivatives, that have various programs, like antiviral Attributes.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for sort 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar levels.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, which are used in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication applied to control variety 2 diabetes by inhibiting 17b)-7-[9-[(4 sodium-glucose co-transporter two (SGLT2).